A new compound being tested on laboratory mice has shown promise in reversing the symptoms of Alzheimer’s. The compound, developed by Saint Louis University, was shown in laboratory settings to restore cognitive functions in animal subjects, Memory and appropriate behavior were restored, and inflammation was reduced in the brain.

Human trials of the compound are still a ways off. First, the compound will have to undergo extensive toxicity tests before it can make the leap to human trials. But, the early results from the study show promise.

The drug compound tested works by blocking the translation of RNA, which triggers a process that keeps an excess of amyloid beta protein from being produced. Yeah, your head is spinning unless you’re a scientist. The English translation of that is that it helps prevent the formation of plaques found in the brains of patients with Alzheimer’s.

Research professor of geriatric at Saint Louis University spoke of the promise of the study. The findings of the study “suggest that an antisense that targets the precursor to amyloid beta protein is a potential therapy to explore to reversing symptoms of Alzheimer’s disease”.

Anything that works to reverse the effects of Alzheimer’s would be huge for patients and the medical community. Families of patients are desperate for a drug therapy that can offer some relief from the debilitating disease.

The compound may be a ways off from human trials, but every study seems to be getting closer and closer to finding a viable treatment for the disease, and hopefully, an eventual cure.


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